Derisk high-stakes decisionsby simulatingpatient adherence
Compound institutional knowledge into AI-powered digital twins of any stakeholder group — then test strategies in minutes, not months.
One Platform,
Three Breakthroughs.
From buried insights to validated decisions in 12 minutes.
Intelligence Hub
Every study you've ever done, instantly queryable. Upload your research archive and ask anything in natural language — with page-level citations and MLR-ready provenance.
Digital Twin Panel
HCP, patient, and payer twins across 10+ therapeutic areas. Talk to any stakeholder segment, any time — built from real behavioral research, not generic training data.
Simulation Lab
Test 100 strategies in 12 minutes, not 12 weeks. Run concepts, messages, and scripts through an entire panel — with audit-ready results and provenance.
You can always see where
it came from.
Most AI platforms give you an answer. PX CortexTM gives you an answer — and the receipt. Every finding is linked to its source in your own research data.
Click it, and it opens to the exact document, page, and passage that generated it. No black box. No wondering whether something was hallucinated. The proof is always one click away.
Providers underestimate patient willingness to try new treatment modalities, creating a perception gap that delays adoption. [14]
Patient Attitudes Study — Treatment Preferences
Willingness scores exceeded provider estimates by 34% [14]
Alignment With Real Patient Research.
In a proof-of-concept study, digital twins independently identified 96% of the same findings as real patients in moderated research sessions.
Built for how pharma teams
actually work.

Your campaign is ready. But is your audience?
Message & Concept Testing
You've spent three months developing a new campaign. Before it goes to print, put it in front of the people who matter — and find out what lands, what falls flat, and what you didn't think to ask.
Competitive Positioning
Your competitor just shifted their messaging. How will your HCPs react? Know before you respond — not after you've committed the budget.
Launch Readiness
A new brand launch touches every team — marketing, field, medical, market access. Validate the full narrative across every audience at once, before anyone goes live.

You're losing patients at enrollment. You just don't know where yet.
Enrollment Flow Optimization
Your enrollment completion rate is 34%. Somewhere in the flow, patients are confused, overwhelmed, or giving up. Find the friction — and fix it before you redesign the entire program.
Call Center Readiness
You're about to launch a new brand and train 250 reps. They can't practice on real patients. Give them realistic conversations with AI patients who push back, ask hard questions, and don't follow the script.
Adherence & Retention
You know some patients will stop treatment. You just don't know which ones, or why. Model the behavioral signals and design interventions that reach the right patients at the right time.

The answer is in your data. You just can't find it.
Research Archive Intelligence
You've commissioned 140 studies over five years. When someone asks 'what do we know about adherence barriers?' — it takes weeks to pull together an answer. It should take minutes.
Cross-Study Pattern Discovery
The insight that changes your strategy isn't in any single study. It's in the pattern across all of them. Surface contradictions, convergence, and knowledge gaps you didn't know existed.
Executive Strategy Sessions
Your leadership team makes decisions with a fraction of available intelligence. Give them an interactive session where they can explore, question, and pressure-test — backed by every study you've ever run.

Every rep walks in prepared. Every conversation is practiced.
HCP Detailing Simulation
Your rep is about to sit across from a skeptical neurologist who has heard every pitch. Let them practice — against a digital twin built from how that type of physician actually thinks, objects, and decides.
FRM Payer Conversations
Field Reimbursement Managers handle the most complex conversations in pharma. Let them rehearse payer objections, prior auth scenarios, and formulary challenges before the meeting that matters.
Market Access Strategy
Each P&T decision affects hundreds of millions in revenue. Simulate the committee's reaction to your value proposition and evidence package before you walk into the room.

Test the experience before anyone experiences it.
Portal & App Usability
Your patient portal is live in three months. Before you commit to the build, walk a diverse panel of patients through every screen — and find out where they get lost, frustrated, or give up.
Digital Flow Testing
Phone trees, chatbot conversations, digital enrollment — every touchpoint is a chance to lose someone. Test each flow with patients who behave like real patients, not QA testers.
Content Comprehension
Consent forms, educational materials, dosing instructions — do your patients actually understand them? Test comprehension across literacy levels, languages, and demographics before you ship.

The street is watching. Be ready for what they'll ask.
Earnings Call Rehearsal
Build digital twins of the analysts who will actually be on the call — with their historical questioning patterns, their obsessions, their skepticism. Rehearse until the narrative holds under pressure.
Crisis Preparedness
A regulatory action, a safety signal, an activist investor. When the crisis hits, your response needs to be tested — not improvised. Simulate the pressure before it's real.
Board & Investor Preparation
Your board has questions you haven't anticipated. Your investors have concerns you haven't addressed. Build their twins. Hear their pushback. Walk in with answers.
25 years of pharma experience.
Built into every interaction.
We've spent decades sitting across the table from patients, HCPs, and brand teams. PX CortexTM was built because we saw, firsthand, how much research value was going unrealized.

Andrew Kucheriavy
Chief Experience & AI Strategist

Stacy Cashman
Digital Health Strategy & Omnichannel

Alex Chudnovsky
AI Strategy & Enterprise Tech

Scott Richardson
Commercial Strategy & Growth

Neeraj Kalani
Go-to-Market & Global Pharma

Emma Wigdahl
Director of Strategy & Research

Allison Bradshaw
Patient Experience Design

Stas Filippov
Senior Interaction Designer & AI

Paola Molina Razo
Senior Behavioral Researcher

Meghan Kocian
Director of Operations & Client Success
Any audience. Any condition.
From neuroscience to oncology, PX CortexTM builds digital twins for any therapeutic area — and expanding weekly.
“This has exceeded all of our expectations.”
Ready to ask your
research a question?
Tell us what you're working on — we'll configure a demo for your therapeutic area and use case.